Indication, Contraindication and Advarse Effect of Atropine :Medicine Review-2022

Indications of atropine:

1. Treatment of OPC poisoning.

2. As anti-spasmodic:

. Gastrointestinal colic.

. Ureteric & biliary colic.

. Peptic ulcer.

. Acute pancreatitis & acute abdomen.

.Dysmenorrhoea.

3. As mydriatics and inflammatory conditions of eye. 4. As pre-anaesthetic medication for bronchodilator & to reduce bronchial secretion.

5. As anti-parkinsonism.

6. As anti-motion sickness.

7. Treatment of sinus bradycardia after MI.

8. Excessive sweating (Hyperhidrosis).

9. In hiccup & chinitis.

Contraindications of atropine:

1. Acute congestive glaucoma.

2. Congestive cardiac failure.

3. Prostatic enlargement (urinary retention).

4. Gastric outlet obstruction (pyloric stenosis)..

5. Chronic lung disease.

Adverse effects of atropine:

1. Skin:

. Hyper-pyrexia (109°F).

. Dryness of skin.

2. GIT :

. Dryness of mouth

. Hoarsence of Voice

. Constipation.

3. Eye:

. Blurring of vission

. My driasis.

. Cycloplegia.

. Loss of light reflex.

.Glucoma.

4.CVS:

.Tachycardia.

. Palpitation..

5. Bladder:

. Retention of urine.

6. Lung:

.Quick & shallow respiration.

7. CNS:

. Restlessness.

. Agitation.

. Excitement.

. Convulsion.

• Confusion.

. Hallucination.

8. Allergic reaction:

. Dermatitis.

. Conjunctivitis.

. Eyelid swelling.